Differentiation Therapy in Thyroid Carcinoma
نویسندگان
چکیده
منابع مشابه
Squamous Cell Differentiation in Metastatic Papillary Thyroid Carcinoma: Metaplastic
Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1) and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...
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The standard therapy for thyroid cancer is total or near total thyroidectomy, followed by the administration of radioactive iodine for remnant ablation or residual disease. Patients with radioiodine therapy are predisposed to second malignant neoplasms in organs such as central nervous system (CNS), breast, prostate, kidney, bone marrow, salivary gland, and digestive tract. Exposure to carcinog...
متن کاملRetrospective analysis of I-131 therapy in patients with follicular carcinoma of the thyroid [Persian]
In research institute for nuclear medicine (Tehran University of Medical Sciences) 50 patients with follicular thyroid carcinoma were evaluted retrospectively. The purpose of the study was assesment of the response of iodine-131 therapy. The best result were achieved when the patient treated with iodine-131 for the first time, in the 4th decade of life, with total thyroidectomy and no met...
متن کاملEffects of early liothyronine consumption after radioiodine therapy on accumulated dose and exposure rate in patients with thyroid carcinoma
Introduction: Patients administered with a therapeutic dose of 131I for thyroid cancer treatment are potential sources of unacceptably high radiation exposure to other individuals, particularly the patient's immediate family members. The aim of this study is to investigate effects of early liothyronine consumption after radio-iodine therapy on accumulated dose and e...
متن کاملManagement of Thyroid carcinoma: Hahnemann experience
The primary treatment of thyroid carcinoma is surgery and the outcome depends on its extent. The post-operative management alternatives in thyroid carcinoma include thyroid hormone, radio-iodine ablation (I-131 Na), external beam radiation therapy (EBRT) and occasionally adjuvant chemotherapy. This retrospective study analyzes the managements of 153 patients (102, 51), age range 10-96 yea...
متن کاملEvaluation of response to I-131 ablative therapy in patients with differentiated thyroid carcinoma: A five year retrospective study [Persian]
Differentiated thyroid carcinomas usually show good uptake and response to I-131 ablative treatment. In this study, 90 patients following near total thyroidectomy who were referred to our institute for I-131 therapy are retrospectively studied. The patients are divided in two groups. Group 1 revealed complete ablation after one dose of I-131. Group 2 needed more than one dose of I-131 for...
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